Inositol phosphate
Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation. The group comprises:
Functions
Inositol triphosphate
Inositol trisphosphates act on the inositol triphosphate receptor to release calcium into the cytoplasm. Further reading: Function of calcium in humans
Other
Inositol tetra-, penta-, and hexa-phosphates have been implicated in gene expression[1] and Steger[2] (both in Science Magazine).
References
- ^ Shen, X; Xiao, H; Ranallo, R; Wu, WH; Wu, C (2003). "Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates". Science 299 (5603): 112–4. doi:10.1126/science.1078068. PMID 12434013.
- ^ Steger, DJ; Haswell, ES; Miller, AL; Wente, SR; O'Shea, EK (2003). "Regulation of chromatin remodeling by inositol polyphosphates". Science 299 (5603): 114–6. doi:10.1126/science.1078062. PMC 1458531. PMID 12434012. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1458531.
External links
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Glycerol backbone
(Glycerophospholipids/
Phosphoglycerides) |
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| Sphingosine backbone |
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| Metabolites |
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mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m
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k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon
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m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
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biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i
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